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Sketchy Biochemistry
2.10 - Homocystinuria - Sketchy Biochemistry
Chapter 1
Metabolism: Carbohydrates
1.1 - Glycolysis Part 1
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1.2 - Glycolysis Part 2
1.3 - Gluconeogenesis
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1.4 - Regulation of PFK-1 and FBPase-1 by F-2_6-BP and During the Fed and Fasting State
1.5 - Pyruvate Dehydrogenase Complex
1.6 - Fates of Pyruvate
1.7 - Pyruvate Dehydrogenase Deficiency and Arsenic Poisoning
1.8 - Glycogen Synthesis - Glycogenesis - and Degradation - Glycogenolysis
1.9 - Hormonal Regulation of Glycogen by Insulin_ Glucagon_ and Epinephrine
1.10 - TCA Cycle
1.11 - Malate-Aspartate and Glycerol-Phosphate Shuttles
1.12 - Electron Transport Chain-Oxidative Phosphorylation
1.13 - Pentose Phosphate Pathway_ G6PD Deficiency
1.14 - Metabolism and Disorders of Galactose
1.15 - Metabolism and Disorders of Fructose and Sorbitol
1.16 - Lactase Deficiency
1.17 - Glycogen Storage Diseases
17 Lessons
Chapter 2
Metabolism: Amino Acids and Proteins
2.1 - Amino Acids - Overview
2.2 - Amino Acid Derivatives
2.3 - Catecholamine Synthesis and Degradation
2.4 - Inborn Errors of Amino Acid Metabolism - Overview - Phenylketonuria - PKU
2.5 - Disorders of Tyrosine Catabolism_ Alkaptonuria
2.6 - Branched-Chain Amino Acid Catabolism_ Maple Syrup Urine Disease
2.7 - Urea Cycle_ Hyperammonemia_ Ornithine Transcarbamylase Deficiency
2.8 - The Cahill and Cori Cycles
2.9 - Organic Acidemias
2.10 - Homocystinuria
10 Lessons
Chapter 3
Metabolism: Lipids
3.1 - Triglyceride Catabolism_ Beta Oxidation of Even-Chain Fatty Acids
3.2 - Beta Oxidation of Odd-Chain Fatty Acids - VOMIT Pathway
3.3 - Ketone Bodies
3.4 - Fatty Acid Synthesis
3.5 - Lipid Digestion and Absorption
3.6 - Lipid Transport - Key Enzymes_ Major Apolipoproteins and Lipoprotein Functions
6 Lessons
Chapter 4
Metabolism: Alcohol Metabolism
4.1 - Alcohol Metabolism
1 Lessons
Chapter 5
Metabolism: Heme and Porphyrias
5.1 - Heme Synthesis
5.2 - Porphyrias
2 Lessons
Chapter 6
Cell Biology: Cell Cycle and Division
1.1 - Cell Cycle
1.2 - Mitosis
1.3 - Meiosis
1.4 - Nondisjunction
4 Lessons
Chapter 7
Cell Biology: Parts of Cell
2.1 - Nucleus_ Ribosomes and Mitochondria
2.2 - Endoplasmic Reticulum_ Vesicles_ and Golgi-Apparatus
2.3 - Collagen - Overview and Synthesis
3 Lessons
Chapter 8
Cell Biology: Lysosomal Storage Diseases
3.1 - Sphingolipidoses Part 1- Tay-Sachs Disease_ Niemann-Pick Disease
3.2 - Sphingolipidoses Part 2- Gaucher Disease_ Metachromatic Leukodystrophy_ Krabbe Disease
3.3 - Sphingolipidoses Part 3- Fabry Disease
3.4 - Mucopolysaccharidoses- Hurler Syndrome_ Hunter Syndrome
4 Lessons
Chapter 9
Molecular Biology: DNA
1.1 - Chromatin Structure
1.2 - DNA Replication
1.3 - DNA Mutations
1.4 - DNA Repair Mechanisms (Nucleotide Excision Repair_ Base Excision Repair_ Nonhomologous End Joining and Homologous Recombination)
1.5 - Purine (De-Novo) and Pyrimidine Synthesis
1.6 - Purine Salvage Pathway
1.7 - Purine Salvage Deficiencies (Adenosine Deaminase Deficiency_ Lesch-Nyhan Syndrome)
1.8 - Lac Operon
8 Lessons
Chapter 10
Molecular Biology: RNA
2.1 - RNA Structure and Function
2.2 - Transcription and RNA Processing
2 Lessons
Chapter 11
Molecular Biology: Protein
3.1 - Protein Synthesis
1 Lessons
Chapter 12
Molecular Biology: Recombinant DNA and Biotechnology
4.1 - Recombinant DNA (Overview)_ Molecular Cloning and Polymerase Chain Reaction
4.2 - Blotting
4.3 - Genomic and cDNA Libraries
4.4 - Biotechnology (Applications_ Safety and Ethics)
4 Lessons
Chapter 13
Vitamins and Minerals: Water Soluble Vitamins
1.1 - Vitamin B1 (Thiamine)
1.2 - Vitamin B2 (Riboflavin)
1.3 - Vitamin B3 (Niacin)
1.4 - Vitamin B5 (Pantothenic Acid)
1.5 - Vitamin B6 (Pyridoxine)
1.6 - Vitamin B7 (Biotin)
1.7 - Vitamin B9 (Folate)
1.8 - Vitamin B12 (Cobalamin)
1.9 - Vitamin C
9 Lessons
Chapter 14
Vitamins and Minerals: Fat Soluble Vitamins
2.1 - Vitamin A
2.2 - Vitamin D
2.3 - Vitamin E
2.4 - Vitamin K
4 Lessons
Chapter 15
Clinical Genetics: Population Genetics
1.1 - Hardy-Weinberg Population Genetics
1 Lessons
Chapter 16
Clinical Genetics: X-linked Dominant Diseases
2.1 - Rett Syndrome
1 Lessons
Chapter 17
Clinical Genetics: Trinucleotide Repeat Diseases
3.1 - Fragile-X Syndrome
1 Lessons
Chapter 18
Clinical Genetics: Trisomy Diseases
4.1 - Down-s Syndrome
4.2 - Edwards and Patau Syndromes
2 Lessons
Chapter 19
Clinical Genetics: Mitochondrial Diseases
5.1 - Mitochondrial Inheritance Disorders
1 Lessons
Chapter 20
Clinical Genetics: Disorders of Imprinting and Microdeletion
6.1 - Disorders of Imprinting (Prader-Willi and Angelman Syndromes)
1 Lessons
Chapter 21
Clinical Genetics: Autosomal Recessive Diseases
7.1 - Autosomal Recessive Diseases
1 Lessons
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